Also, like you said they think a pill can solve everything and maybe they get incentives from pharmacuetical companies to push pills, but it is more like it is easy to prescribe a pill and harder to think about what it could really be. Dosage for Gastroesophageal Reflux Disease Associated With a History of Erosive Esophagitis. The recommended adult dosage of PROTONIX I.V. is 40 mg given once daily by intravenous infusion for 7 to 10 days. Pantoprazole (Protonix ®) The authors make no claims of the accuracy of the information contained herein; and these suggested doses and/or guidelines are not a substitute for clinical judgment. Pantoprazole sodium is a white to off-white crystalline powder and is racemic. Pantoprazole has weakly basic and acidic properties. Pantoprazole sodium is freely soluble in water, very slightly soluble in phosphate buffer at pH 7.4, and practically insoluble in n-hexane. They can't give an IV push and leave the room. I meant tha with the current practice of IVPB administration of this drug the nurse can leave room. I meant tha with the current practice of IVPB administration of this drug the nurse can leave room. I frequently administer Protonix 40 mg IV (in 50 ml NSS) to patients, and when it first came out a while back, we had to change IV tubing with each Protonix piggyback we hung and it also came with its own filter. Friend of mine is working with a preceptor who wants to know why you can't give IV protonix faster than two minutes IVP.We've looked everywhere and can't find the answer. Gastroesophageal Reflux Disease Associated with a History of Erosive Esophagitis. Protonix I.V. is indicated for short-term treatment (7 to 10 days) of adult patients with gastroesophageal reflux disease (GERD) and a history of erosive esophagitis (EE). If you have to give it IV, give through a PICC or CL and infuse it in a bag of saline. There is no reversal for the extravasation and the tissue damage can lead to amputation. There is no reversal for the extravasation and the tissue damage can lead to amputation. How to use Protonix IV Vial. This medication is given by injection into a vein as directed by your doctor. The dosage and length of treatment are based on your medical condition and response to.